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Anatomical Landmark-Guided Deep Reinforcement Learning for Autonomous Gastric Navigation

Summary

A research team proposes the AL-DRL framework for autonomous gastric navigation using wireless capsule endoscopy. It leverages stable landmark coordinates to achieve over 97% coverage in simulations within 50 seconds and 87% coverage in ex-vivo experiments, reducing procedure time by 53% compared to expert manual control. The method significantly outperforms standard DRL agents.

SourcearXiv RoboticsAuthor: Haoxuan Wu, Sishen Yuan, Haitao Gao, Zhen Li, Xiuli Zuo, Hongliang Ren
Anatomical Landmark-Guided Deep Reinforcement Learning for Autonomous Gastric Navigation
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[2605.08269] Anatomical Landmark-Guided Deep Reinforcement Learning for Autonomous Gastric Navigation

[Submitted on 8 May 2026]

Title:Anatomical Landmark-Guided Deep Reinforcement Learning for Autonomous Gastric Navigation

View a PDF of the paper titled Anatomical Landmark-Guided Deep Reinforcement Learning for Autonomous Gastric Navigation, by Haoxuan Wu and 5 other authors

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Abstract:Wireless capsule endoscopy (WCE) enables painless visualization of the gastrointestinal tract, but its diagnostic potential is limited by incomplete mucosal coverage and poor transferability of existing navigation methods across patient anatomies. We propose a transferable, anatomical landmarkguided deep reinforcement learning (AL-DRL) framework for autonomous gastric navigation. Leveraging a lightweight edgecontour-depth fusion module, our policy operates on stable, lowdimensional landmark coordinates rather than high-dimensional video streams, effectively bridging the sim-to-real gap. In simulations across eight patient-derived models, the method achieves over 97% coverage within 50 seconds, significantly outperforming vanilla PPO, SAC, and DQN agents. A two-stage sim-to-real pipeline with an adaptive dynamic programming controller actively mitigates physical disturbances. Ex-vivo experiments demonstrate a mean coverage of 87% and a 53% reduction in procedure time compared with expert manual control.

Subjects:

Robotics (cs.RO); Systems and Control (eess.SY)

Cite as: arXiv:2605.08269 [cs.RO]

(or arXiv:2605.08269v1 [cs.RO] for this version)

https://doi.org/10.48550/arXiv.2605.08269

arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Sishen Yuan [view email] [v1] Fri, 8 May 2026 03:11:21 UTC (12,087 KB)

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Key points and analysis

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EngineersIntermediate

Key points

  • AL-DRL uses low-dimensional anatomical landmark coordinates to bridge the sim-to-real gap.
  • Simulations across eight patient models achieve over 97% coverage within 50 seconds.
  • A two-stage sim-to-real pipeline with adaptive control mitigates physical disturbances.
  • Ex-vivo experiments show 87% coverage and 53% reduction in procedure time.

Highlights and analysis are generated automatically and may contain errors. Check the original source.