[Submitted on 3 Oct 2026]
Title:UniPro: Unified Multi-Mode Medical Image Segmentation from 2D Images to 3D Volumes via Propagation
View a PDF of the paper titled UniPro: Unified Multi-Mode Medical Image Segmentation from 2D Images to 3D Volumes via Propagation, by Bangwei Guo and 7 other authors
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Abstract:Medical image segmentation remains fragmented along two axes: segmentation paradigms and data dimensionality. Existing methods are typically developed separately for semantic, in-context, and interactive segmentation, and are further specialized to either native 2D images or 3D volumetric data. In clinical practice, however, segmentation workflows take many forms: a case may be initialized by semantic prediction, reference-guided segmentation, or user interaction. Regardless of how it begins, fine-grained refinement is naturally performed on 2D views; for volumetric scans, such 2D edits must propagate coherently to the rest of the volume. We present UniPro, a unified model that bridges segmentation paradigms and data dimensionality, using propagation to extend 2D segmentation to 3D volumes. Our key insight is that volumetric propagation and in-context segmentation share the same reference-conditioned prediction mechanism, differing only in whether the reference image-mask pairs come from other cases or from previously segmented neighboring slices. Building on this view, UniPro supports semantic, in-context, interactive, and propagation-based segmentation within a single slice-based framework, using class priors, reference exemplars, user clicks, and neighboring-slice predictions as mode-specific conditioning inputs. To improve propagation reliability, UniPro further incorporates bidirectional and 3D supervision to regularize slice-wise propagation beyond per-slice losses. Extensive experiments across diverse modalities and anatomies show that UniPro achieves strong performance across all segmentation settings, enabling annotation-efficient 3D segmentation from sparse 2D initialization and reducing slice-by-slice correction effort.
Subjects:
Computer Vision and Pattern Recognition (cs.CV)
Cite as: arXiv:2610.06938 [cs.CV]
(or arXiv:2610.06938v1 [cs.CV] for this version)
https://doi.org/10.48550/arXiv.2610.06938
arXiv-issued DOI via DataCite (pending registration)
Submission history
From: Bangwei Guo [view email] [v1] Sat, 3 Oct 2026 06:41:17 UTC (5,666 KB)
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