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PRISM-CTG: A Foundation Model for Cardiotocography Analysis with Multi-View SSL

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PRISM-CTG is a novel self-supervised foundation model that leverages large-scale unlabelled cardiotocography (CTG) recordings to learn transferable domain-level representations. It uses a multi-view self-supervised framework jointly optimizing three complementary pretext objectives: random-projected guided masked signal reconstruction, clinical variable prediction, and feature classification. The model outperforms baselines on 7 downstream CTG tasks and demonstrates strong generalization on external datasets, marking the first large-scale foundation model for CTG.

SourcearXiv Machine LearningAuthor: Sheng Wong, Ravi Shankar, Beth Albert, Hao Fei, Lin Li, Imane Ben M'Barek, Manu Vatish, Gabriel Davis Jones
PRISM-CTG: A Foundation Model for Cardiotocography Analysis with Multi-View SSL
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[2605.02917] PRISM-CTG: A Foundation Model for Cardiotocography Analysis with Multi-View SSL

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Computer Science > Machine Learning

arXiv:2605.02917 (cs)

[Submitted on 9 Apr 2026]

Title:PRISM-CTG: A Foundation Model for Cardiotocography Analysis with Multi-View SSL

Authors:Sheng Wong, Ravi Shankar, Beth Albert, Hao Fei, Lin Li, Imane Ben M'Barek, Manu Vatish, Gabriel Davis Jones

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Abstract:Supervised deep learning models for automated CTG analysis are typically constrained by narrowly curated labelled datasets and limited patient cohorts, leaving substantial volumes of physiologically informative clinical recordings untapped. To address this limitation, we propose Physiology-aware Representation Learning via Integrated Self-supervision and Metadata for CTG (PRISM-CTG), a clinically grounded self-supervised foundation model (FM) for CTG that leverages large-scale unlabelled recordings to learn transferable domain-level representations. PRISM-CTG is pretrained using a multi-view self-supervised framework that jointly optimises 3 complementary pretext objectives: random-projected guided masked signal reconstruction, clinical variable prediction, and feature classification. Each objective is associated with a dedicated task-specific token, enabling specialised representation learning, while controlled cross-attention facilitates information exchange across clinical context. By reframing patient metadata and domain knowledge, which are often underutilised in conventional training as prediction targets, Prism-CTG transforms readily available clinical information into additional supervisory targets that guide clinically meaningful representation learning. Extensive experiments across 7 downstream CTG tasks in both antepartum and intrapartum domains demonstrated that PRISM-CTG consistently outperforms in-domain and SSL baselines. Notably, PRISM-CTG demonstrated strong generalisation under external validation on 2 datasets, while achieving comparable performance to studies trained on substantially larger, privately labelled datasets. To our knowledge, this is the first study to introduce large-scale FM for CTG that learns domain-level representations.

Subjects:

Machine Learning (cs.LG); Artificial Intelligence (cs.AI)

Cite as: arXiv:2605.02917 [cs.LG]

(or arXiv:2605.02917v1 [cs.LG] for this version)

https://doi.org/10.48550/arXiv.2605.02917

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arXiv-issued DOI via DataCite

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From: Sheng Wong Dr [view email] [v1] Thu, 9 Apr 2026 10:44:27 UTC (5,546 KB)

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Key points

  • PRISM-CTG employs multi-view SSL with masked signal reconstruction, clinical variable prediction, and feature classification.
  • It transforms patient metadata into supervisory signals, guiding clinically meaningful representation learning.
  • Consistently outperforms in-domain and SSL baselines across 7 antepartum and intrapartum CTG tasks.
  • First large-scale foundation model for CTG, achieving strong generalization on external validation datasets.

Highlights and analysis are generated automatically and may contain errors. Check the original source.