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Who Gets Missed in the Tail? Thresholded Subgroup Underdiagnosis in Long-Tailed Chest X-ray Classification

Summary

In chest X-ray classification, acceptable ranking performance can still miss rare-positive patients below threshold, especially within subgroups. Using a diagnostic ladder, group-tail weighting followed by tail-aware thresholding reduces tail FNR from 0.665 to 0.269, but residual missed rates remain high. Fairness depends on finding, subgroup, and threshold jointly.

SourcearXiv Machine LearningAuthor: Ha-Hieu Pham, Hai-Dang Nguyen, Dang P. M. Cao, Thanh-Huy Nguyen, Min Xu, Trung-Nghia Le, Ulas Bagci, Huy-Hieu Pham
Who Gets Missed in the Tail? Thresholded Subgroup Underdiagnosis in Long-Tailed Chest X-ray Classification
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[Submitted on 4 Jul 2026]

Title:Who Gets Missed in the Tail? Thresholded Subgroup Underdiagnosis in Long-Tailed Chest X-ray Classification

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Abstract:In chest X-ray (CXR) classification, acceptable ranking performance can still leave rare-positive patients below threshold, especially within subgroups. We study this pre-deployment fairness problem as an audit question: after a long-tailed multi-label CXR model is converted from scores into decisions, who is missed? Across VinDr-CXR and MIMIC-CXR/CXR-LT, we use a diagnostic ladder to separate class-level long-tail losses, subgroup-aware weighting, group robustness, and threshold selection. On VinDr-CXR, group-tail weighting followed by tail-aware thresholding reduces tail FNR from 0.665 to 0.269, sex worst-group FNR from 0.705 to 0.157, and age worst-group FNR from 0.822 to 0.133, while macro-mAP increases from 0.611 to 0.635. On MIMIC-CXR/CXR-LT, the same score-to-threshold comparison reduces tail FNR from 0.866 to 0.741 and lowers worst-group FNR across sex, age, race, and insurance; residual missed-positive rates nevertheless remain high. Paired bootstrap contrasts on VinDr support the thresholded FNR reductions, and GroupDRO reference runs indicate that aggregate group robustness alone does not remove rare subgroup misses in this setting. The study supports a narrow audit claim: rare-label fairness in CXR depends jointly on the finding, subgroup, and operating threshold, not on label frequency or ranking metrics alone.

Subjects:

Machine Learning (cs.LG); Computer Vision and Pattern Recognition (cs.CV)

Cite as: arXiv:2607.07717 [cs.LG]

(or arXiv:2607.07717v1 [cs.LG] for this version)

https://doi.org/10.48550/arXiv.2607.07717

arXiv-issued DOI via DataCite

Submission history

From: Ha-Hieu Pham [view email] [v1] Sat, 4 Jul 2026 10:30:32 UTC (63 KB)

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Key points and analysis

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Key points

  • Long-tailed multi-label CXR models may miss rare-positive patients in subgroups when converting scores to decisions.
  • A diagnostic ladder approach with group-tail weighting and threshold adjustment reduced tail FNR from 0.665 to 0.269 on VinDr-CXR.
  • Worst-group FNR improved but residual missed rates remained high.
  • Rare-label fairness in CXR depends on the joint effect of finding, subgroup, and operating threshold.

Highlights and analysis are generated automatically and may contain errors. Check the original source.