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Who Became Financially Vulnerable After COVID-19? A Population-Level Machine Learning Analysis Using MEPS Data

This study examines healthcare financial vulnerability before and after the COVID-19 pandemic using MEPS data from 2019 and 2021. High financial burden was defined as out-of-pocket spending exceeding 10% of family income. Poverty status, insurance coverage, and prescription drug spending were strongly associated with vulnerability. Models trained on pre-pandemic data showed only modest performance declines when applied to post-pandemic data, indicating stable predictors.

SourcearXiv Machine LearningAuthor: Alexey Kresin, Zien Cheng, Ammar Ahad, Ebiyomare Kelvin, Manish Sivaratri, Prabhjeet Singh, Omar Aljawfi, Olabisi Ojo, Nawar Shara

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COVID-19 e-print

Important: e-prints posted on arXiv are not peer-reviewed by arXiv; they should not be relied upon without context to guide clinical practice or health-related behavior and should not be reported in news media as established information without consulting multiple experts in the field.

[Submitted on 16 Jul 2026]

Title:Who Became Financially Vulnerable After COVID-19? A Population-Level Machine Learning Analysis Using MEPS Data

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Abstract:The cost of healthcare remains a concern in the United States and may have been influenced by disruptions associated with the COVID-19 pandemic. This study examines healthcare financial vulnerability before and after the pandemic using Medical Expenditure Panel Survey (MEPS) data from 2019 and 2021. High financial burden was defined as out-of-pocket healthcare expenditures exceeding 10% of family income. Survey-weighted subgroup analyses were performed to obtain nationally representative estimates across demographic and socioeconomic groups.

Descriptive analyses were complemented by interpretable logistic regression and machine learning models. Logistic regression was used to estimate adjusted odds ratios, while random forest and gradient boosting models were used to evaluate predictive performance. Temporal generalization assessed whether models trained on pre-pandemic data remained predictive when applied to post-pandemic observations.

Financial vulnerability was strongly associated with poverty status, insurance coverage, and prescription drug spending. Subgroup analyses indicated persistent disparities across population groups, with some evidence of increased burden among vulnerable populations in 2021. Despite these differences, models trained on pre-pandemic data exhibited only modest reductions in predictive performance when evaluated on post-pandemic data, suggesting that the principal predictors of healthcare financial vulnerability remained relatively stable over time.

These findings provide a population-level assessment of healthcare financial vulnerability during the COVID-19 period and demonstrate the value of combining interpretable statistical modeling with machine learning for population health research. The results may support future population health surveillance, risk stratification, and healthcare policy research aimed at reducing financial barriers to care.

Comments: 14 pages, 3 figures

Subjects:

Machine Learning (cs.LG)

Cite as: arXiv:2607.15446 [cs.LG]

(or arXiv:2607.15446v1 [cs.LG] for this version)

https://doi.org/10.48550/arXiv.2607.15446

arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Alexey Kresin [view email] [v1] Thu, 16 Jul 2026 20:38:26 UTC (1,486 KB)

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