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Two-Parameter Flow Map Learning for Continuous-Time Diffeomorphic Image Registration

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arXiv:2609.10789v1 Announce Type: new Abstract: Diffeomorphic image registration is central to medical image analysis, enabling anatomically consistent alignment across subjects. Most learning-based diffeomorphic methods model autonomous ODEs(ordinary differential equations) by parameterizing a stationary velocity field and recovering deformations via scaling-and-squaring. While non-autonomous ODEs with time-dependent velocities increase expressiveness, existing approaches rely on numerical integration to implicitly enforce flow structure that entangles model expressiveness with discretization accuracy. We propose a framework to directly learn the continuous-time solution of a non-autonomous ODE formulated as a two-parameterflow map. By enforcing cocycle consistency, a fundamental structu…

SourcearXiv Computer VisionAuthor: Mohammadjavad Matinkia, Nilanjan Ray
Two-Parameter Flow Map Learning for Continuous-Time Diffeomorphic Image Registration
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[Submitted on 9 Sep 2026]

Title:Two-Parameter Flow Map Learning for Continuous-Time Diffeomorphic Image Registration

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Abstract:Diffeomorphic image registration is central to medical image analysis, enabling anatomically consistent alignment across subjects. Most learning-based diffeomorphic methods model autonomous ODEs(ordinary differential equations) by parameterizing a stationary velocity field and recovering deformations via scaling-and-squaring. While non-autonomous ODEs with time-dependent velocities increase expressiveness, existing approaches rely on numerical integration to implicitly enforce flow structure that entangles model expressiveness with discretization accuracy. We propose a framework to directly learn the continuous-time solution of a non-autonomous ODE formulated as a two-parameterflow map. By enforcing cocycle consistency, a fundamental structural property of time-varying flows, we learn the flow maps without time discretization and velocity integration during training. The framework recovers diffeomorphic mappings at inference using a small number of compositions. Our proposed framework seamlessly incorporates standard registration backbones and improves alignment accuracy consistently across nine datasets while preserving diffeomorphic structure. Notably, the proposed method achieves an average Dice improvement of 2.1% on brain MRI benchmarks, a 12% TRE reduction on lung CT, and a 2.6% Dice gain on cardiac MRI and ultrasound datasets.

Comments: Published at European Conference on Computer Vision (ECCV), 2026

Subjects:

Computer Vision and Pattern Recognition (cs.CV)

ACM classes: I.4.9

Cite as: arXiv:2609.10789 [cs.CV]

(or arXiv:2609.10789v1 [cs.CV] for this version)

https://doi.org/10.48550/arXiv.2609.10789

arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Mohammadjavad Matinkia [view email] [v1] Wed, 9 Sep 2026 19:52:48 UTC (23,057 KB)

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  • AI generation is temporarily unavailable; this entry was preserved with deterministic fallback metadata.
  • arXiv:2609.10789v1 Announce Type: new Abstract: Diffeomorphic image registration is central to medical image analysis, enabling anatomically consistent alignment across subjects.…

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