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Scaling Multi-Teacher Distillation for Digital Pathology

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arXiv:2610.12574v1 Announce Type: new Abstract: Multi-teacher distillation allows transferring knowledge from multiple "teacher" networks to a single "student" network. This method is promising in fields such as digital pathology, where many powerful foundation models were proposed recently. However, as we show in this paper, the standard multi-teacher distillation approach reacts poorly to an increase in the number of teachers used to train a student encoder. We demonstrate that learning teacher-specific representations is a key to scaling in MTD. Importantly, different design choices, such as learnable teacher tokens, a tailored attention scheme, additional mixture-of-experts layers and a contrastive loss, are proposed to better learn such teacher-specific representations. We show that…

SourcearXiv Computer VisionAuthor: Sofi\`ene Boutaj, Pierre Marza, Varun Belagali, Dimitris Samaras, Maria Vakalopoulou, Stergios Christodoulidis
Scaling Multi-Teacher Distillation for Digital Pathology
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[Submitted on 8 Oct 2026]

Title:Scaling Multi-Teacher Distillation for Digital Pathology

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Abstract:Multi-teacher distillation allows transferring knowledge from multiple "teacher" networks to a single "student" network. This method is promising in fields such as digital pathology, where many powerful foundation models were proposed recently. However, as we show in this paper, the standard multi-teacher distillation approach reacts poorly to an increase in the number of teachers used to train a student encoder. We demonstrate that learning teacher-specific representations is a key to scaling in MTD. Importantly, different design choices, such as learnable teacher tokens, a tailored attention scheme, additional mixture-of-experts layers and a contrastive loss, are proposed to better learn such teacher-specific representations. We show that our method better scales with respect to the number of considered teachers, allowing us to train compact student encoders, up to 10x more efficient than larger teacher foundation models, while matching their performance and even outperforming them on a large set of tile-level and slide-level tasks. We conduct a thorough empirical validation, evaluating more than 10 foundation models on 39 tasks spanning tile and slide levels. As a result, we release a new collection of strong and efficient foundation models, named OMNI, trained from the knowledge of 10 state-of-the-art foundation models. We finally conduct an analysis of the learned teacher-specific representations, highlighting their complementarity and explaining why they can be easily aggregated at downstream time.

Comments: Accepted at NeurIPS 2026. Project page: this https URL

Subjects:

Computer Vision and Pattern Recognition (cs.CV)

Cite as: arXiv:2610.12574 [cs.CV]

(or arXiv:2610.12574v1 [cs.CV] for this version)

https://doi.org/10.48550/arXiv.2610.12574

arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Sofiène Boutaj [view email] [v1] Thu, 8 Oct 2026 18:02:09 UTC (8,138 KB)

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  • AI generation is temporarily unavailable; this entry was preserved with deterministic fallback metadata.
  • arXiv:2610.12574v1 Announce Type: new Abstract: Multi-teacher distillation allows transferring knowledge from multiple "teacher" networks to a single "student" network. This metho…

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