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PathoJev: Efficient Pathology Decisions from Shared Visual Context

Summary

PathoJev is a pathology AI model that directly predicts answer probabilities for multiple structured questions about a slide by encoding it once and reusing recurrent states, accelerating whole-slide and region-level assessment. On three whole-slide benchmarks, the 9B and 27B models achieve mean accuracies of 77.2% and 78.1%, exceeding SlideChat by 5.4 and 6.3 percentage points. On WSI-Bench, the 9B model runs 9.1x faster than SlideChat, and shared context accelerates 64-question workloads by up to 11.2x.

SourcearXiv Computer VisionAuthor: Chengyang Zhang, Wenchuan Zhang, Bo Li, Xinyu Liu, Jiaming Yang, Mengran Li, Jie Chen, Wei Ju, Yuhao Yi, Hong Bu, Jiancheng Lv
PathoJev: Efficient Pathology Decisions from Shared Visual Context
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[Submitted on 29 Oct 2026]

Title:PathoJev: Efficient Pathology Decisions from Shared Visual Context

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Abstract:Pathology workflows require multiple visual judgments about the same slide, from identifying tumor type to assessing grade and invasion. Generating and parsing a separate textual response for each structured question adds latency between visual evidence and usable decisions. Building on the System One paradigm, we introduce PathoJev, a pathology model that directly predicts answer probabilities for whole-slide and region-level assessment. PathoJev encodes each slide once and evaluates independent question suffixes in batches over the shared visual context. Reusing the hybrid backbone's recurrent states further limits the computation that grows with slide-context length for each additional question. Across three whole-slide benchmarks, the 9B and 27B models achieve mean accuracies of 77.2% and 78.1%, exceeding SlideChat by 5.4 and 6.3 percentage points. Both scales also maintain competitive accuracy on five ROI benchmarks. On WSI-Bench, the 9B model runs 9.1x faster than SlideChat. Shared context accelerates eight-question workloads by 6.9x and 5.9x over separate prefix encoding, rising to 11.2x and 8.9x for 64 questions. These results provide a reusable probabilistic interface for combining multiple visual judgments in whole-slide and local tissue assessment. Code: this https URL.

Subjects:

Computer Vision and Pattern Recognition (cs.CV)

Cite as: arXiv:2610.40752 [cs.CV]

(or arXiv:2610.40752v1 [cs.CV] for this version)

https://doi.org/10.48550/arXiv.2610.40752

arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Chengyang Zhang [view email] [v1] Thu, 29 Oct 2026 16:14:49 UTC (10,397 KB)

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Key points

  • PathoJev encodes each slide once and evaluates multiple question suffixes in batches over the shared visual context.
  • The 9B and 27B models achieve mean accuracies of 77.2% and 78.1% on three whole-slide benchmarks, outperforming SlideChat.
  • On WSI-Bench, the 9B model is 9.1x faster than SlideChat; shared context speeds up 64-question workloads by up to 11.2x.
  • Code is available on GitHub.

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