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Partial Information Decomposition as a Multi-Contrast 3D MRI Selection Strategy for Resource-Constrained Deep Neural Network Training in Brain Tumor Segmentation

A Partial Information Decomposition (PID) framework is used to select the most informative MRI contrast pair prior to training, reducing computational cost for multi-contrast 3D brain tumor segmentation. Applied to T1n, T1c, T2w, and T2-FLAIR, it selected T1c+T2-FLAIR, which achieved mean Dice 0.676 vs 0.687 for all four inputs on lightweight 3D U-Nets.

SourcearXiv Computer VisionAuthor: Agamdeep Chopra, Mehmet Kurt

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[Submitted on 16 Jul 2026]

Title:Partial Information Decomposition as a Multi-Contrast 3D MRI Selection Strategy for Resource-Constrained Deep Neural Network Training in Brain Tumor Segmentation

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Abstract:Multi-contrast 3D MRI segmentation can be computationally demanding when all available sequences are used. We evaluate a pre-training Partial Information Decomposition framework that ranks input pairs according to their redundant, unique, and synergistic information about regional tumor burden and selects the highest-ranked pair for downstream training. Applied to T1n, T1c, T2w, and T2-FLAIR MRI, the framework selected T1c+T2-FLAIR. We then trained eleven architecturally identical lightweight 3D U-Nets using different input configurations. On an independent test cohort, T1c+T2-FLAIR was the strongest two-input configuration and ranked second overall in mean Dice (0.676 versus 0.687 for all four inputs). Independent Shapley analysis on the full-input model also identified T2-FLAIR and T1c as the most influential inputs and their pairwise interaction as the strongest. These findings demonstrate the practical value of PID based pre-training selection for identifying compact, informative MRI input sets before costly 3D model development.

Subjects:

Computer Vision and Pattern Recognition (cs.CV); Artificial Intelligence (cs.AI)

Cite as: arXiv:2607.15396 [cs.CV]

(or arXiv:2607.15396v1 [cs.CV] for this version)

https://doi.org/10.48550/arXiv.2607.15396

arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Agamdeep Chopra [view email] [v1] Thu, 16 Jul 2026 18:53:41 UTC (358 KB)

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