HPE AI Factory With NVIDIA Expands for the Era of Agents

Enterprises are moving agentic AI from proof of concept to production — and the next generation of AI factories are built for the era of agents.

At HPE Discover Las Vegas, running through Thursday, June 18, NVIDIA and HPE are expanding the HPE AI Factory with NVIDIA, including NVIDIA Vera CPU and NVIDIA Agent Toolkit for HPE Private Cloud AI.

Plus, NVIDIA Confidential Computing extends across HPE AI Factory and enhanced full-stack NVIDIA integration — with NVIDIA accelerated computing, NVIDIA AI software and NVIDIA networking — is available throughout the entire portfolio.

NVIDIA Vera CPU Available With HPE Private Cloud AI

The HPE ProLiant Compute DL394 Gen12 with the NVIDIA Vera CPU will be available in 2027 with HPE Private Cloud AI, a turnkey AI factory co-engineered with NVIDIA. Vera is the first CPU built for agents — designed for the tool calls, orchestration and real-time data processing required across the agent loop — bringing deterministic, low-latency performance into HPE Private Cloud AI.

The New York Stock Exchange, in collaboration with Redpanda and HPE, is an early enterprise customer exploring Vera CPU with the HPE ProLiant Compute DL394 Gen12 server.

The Vera CPU is part of the NVIDIA Vera Rubin platform, which is ramping into full production with the NVIDIA Vera Rubin NVL72 rack-scale system available from HPE. Vera Rubin was built for frontier-scale models larger than 1 trillion parameters and will ship with full-stack NVIDIA Confidential Computing across every chip.

HPE is also bringing the HPE Compute XD700 — built on NVIDIA HGX Rubin NVL8 — to the HPE AI Factory, supporting up to 128 Rubin GPUs per rack.

NVIDIA Agent Toolkit Now Available With HPE Private Cloud AI

NVIDIA Agent Toolkit — including NVIDIA Nemotron open models, the NVIDIA OpenShell secure runtime and NVIDIA NemoClaw blueprints — will be available with HPE Private Cloud AI. Together, they give enterprises an agentic AI operating system for monitoring agent behavior, enforcing governance policies, and safely building and running autonomous, long-running multi-agent systems.

HPE Private Cloud AI adds secure local agent registration, letting customers approve AI models, skills and tools against centralized governance and security policies before they run. New HPE Zerto Software capabilities detect rogue agent actions and use continuous data protection to rewind to a clean state.

On the data side, HPE Alletra Storage MP X10000 — which achieved the foundation level of NVIDIA-Certified Storage — automatically applies metadata and governance policies to prepare unstructured data for AI pipelines, improving token throughput.

NVIDIA Confidential Computing Across All HPE AI Factory Solutions

NVIDIA Confidential Computing is now available across the HPE AI Factory through HPE Services — including HPE AI Factory at Scale, HPE Sovereign AI Factory and HPE Private Cloud AI.

AI applications access and use private and sensitive data that needs to be protected and secured. In addition, models trained with proprietary data or techniques need to be safeguarded from exfiltration. Confidential computing is essential for these modern AI workloads, as it protects models and private data during execution for on-premises and sovereign deployments, establishing a chain of trust through cryptographic attestation and encryption at every stage.

In addition, HPE ProLiant Compute DL380a achieved certification as part of the NVIDIA-Certified Systems for NVIDIA Confidential Computing program, which validates robust application performance with confidential computing. These systems provide hardware-based protection for AI workloads and sensitive data assets while maintaining optimal NVIDIA acceleration.

Across the HPE AI Factory solutions, NVIDIA BlueField DPUs and NVIDIA DOCA provide in-silicon zero-trust policy enforcement, runtime threat detection and network encryption — protecting AI workloads, agents and data without performance tradeoffs.

Enhanced Full-Stack NVIDIA Integration Across the Portfolio

HPE AI Factory at Scale, HPE Sovereign AI Factory and HPE Private Cloud AI are now available with NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs, NVIDIA Spectrum-X Ethernet networking, NVIDIA BlueField-3 DPUs and NVIDIA ConnectX-8 SuperNICs.

For next-generation AI factories, every Vera Rubin NVL72 system will ship with NVIDIA networking built in — NVIDIA Vera BlueField-4 DPUs, NVIDIA ConnectX-9 SuperNICs and NVIDIA Spectrum-X Ethernet — with NVIDIA Spectrum-6 switching delivering 1.6x higher networking performance for AI communication versus off-the-shelf Ethernet.

Spectrum-X Ethernet networking is the standard for HPE AI Factory with NVIDIA — including at-scale, sovereign and turnkey AI factory solutions available now. For large-scale and sovereign workloads, HPE announced at NVIDIA GTC in March that it’s also adding NVIDIA InfiniBand networking options — including NVIDIA Quantum-X800 InfiniBand with the HPE Cray Supercomputing GX5000.

These configurations are based on NVIDIA reference architectures and support use cases from AI development through production-scale deployment, with NVIDIA AI Enterprise software and the HPE Unleash AI ecosystem.

At HPE Discover this week, the Unleash AI partner program is expanding with nearly a dozen new AI software partners — including Aizen, BridgeTEK, deepset, Deliverance, Faclon Labs, Gallop, Rocket, Supervity, Thales, Trustwise and Vortiqx.

Attendees can explore these solutions all week at the show and learn more about the HPE AI Factory with NVIDIA, part of the NVIDIA AI Computing by HPE portfolio.