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From ML Predictions to Informed Diagnostic Assistance Using the Toulmin Model of Argumentation

This paper proposes a structured diagnostic assistance framework based on the Toulmin model of argumentation, decomposing image-based ML diagnoses into claim, grounds, warrant, qualifier, rebuttal, and backing. Using a specialized biomarker extractor, a MedGemma agent for medical knowledge, and MedSigLip for image similarity, the system presents human experts with interpretable components for critical assessment of ML outputs.

SourcearXiv AIAuthor: Anca Marginean, Adrian Groza

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[Submitted on 1 May 2026]

Title:From ML Predictions to Informed Diagnostic Assistance Using the Toulmin Model of Argumentation

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Abstract:To provide a structured and interpretable assessment, we decompose the image-based diagnosis into components following the Toulmin model of argumentation. This model consists of a claim, grounds, warrant, qualifier, rebuttal, and backing. Consider a claim generated by a machine learning (ML) model for retinal diagnosis. Rather than accepting this claim at face value, one could either apply explainable AI (XAI) methods or adopt an argumentation-based approach. In our framework, a model specialized in biomarker extraction from images provides the grounds. The warrant-linking the grounds to the claim - is analyzed by an agent equipped with medical knowledge; in our architecture, this role is fulfilled by a MedGemma agent. The qualifier is determined based on the overall quantitative evaluation of both the warrant and grounds models. Finally, a rebuttal is constructed using image similarity measures computed with MedSigLip. All these components are presented to the human expert, enabling a more informed and critical assessment of the ML-generated diagnosis.

Subjects:

Artificial Intelligence (cs.AI); Computer Vision and Pattern Recognition (cs.CV)

Cite as: arXiv:2607.09664 [cs.AI]

(or arXiv:2607.09664v1 [cs.AI] for this version)

https://doi.org/10.48550/arXiv.2607.09664

arXiv-issued DOI via DataCite

Submission history

From: Adrian Groza [view email] [v1] Fri, 1 May 2026 06:58:17 UTC (2,895 KB)

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