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[Submitted on 22 Jul 2026] Title:HERMES: Contrast-Aware Knowledge Graph Reasoning from Clinical Notes for Patient Outcome Prediction View a PDF of the paper titled HERMES: Contrast-Aware Knowledge Graph Reasoning from Clinical Notes for Patient Outcome Prediction, by Gia-Bach Nguyen and 7 other authors View PDF HTML (experimental) Abstract:Clinical predictive models often rely on structured Electronic Health Record data, such as time-series and procedure codes. While recent approaches have begun leveraging unstructured clinical notes, they typically encode them as flat sequences, which may lose explicit relational and temporal structure present in clinical narratives. In response, we propose HERMES, a graph-based framework that operates exclusively on clinical text while preserving clinical relationships. This approach builds on two key ideas. First, personalized Knowledge Graphs (KGs) are constructed through Large-Language-Model-guided extraction from clinical notes with Contrastive Logic Modeling that explicitly captures temporal dynamics and treatment failures and changes in outcomes. Second, a Graph Attention Network synthesizes patient representations through graph-based learning over the KGs. Experiments on MIMIC-III and MIMIC-IV for in-hospital mortality and 30-day readmission prediction show that HERMES consistently outperforms strong text-only baselines. Our findings demonstrate that explicit relational modeling with Contrastive Logic Modeling significantly advances predictive performance. Comments: 12 pages, 4 figures, The 15th Conference on Information Technology and its Applications Subjects: Computation and Language (cs.CL); Machine Learning (cs.LG) Cite as: arXiv:2609.20825 [cs.CL] (or arXiv:2609.20825v1 [cs.CL] for this version) https://doi.org/10.48550/arXiv.2609.20825 arXiv-issued DOI via DataCite Submission history From: Ha Nguyen [view email] [v1] Wed, 22 Jul 2026 09:00:41 UTC (2,394 KB) Full-text links: Access Paper: View a PDF of the paper titled HERMES: Contrast-Aware Knowledge Graph Reasoning from Clinical Notes for Patient Outcome Prediction, by Gia-Bach Nguyen and 7 other authors View PDF HTML (experimental) TeX Source view license Current browse context: cs.CL new | recent | 2026-09 Change to browse by: cs cs.LG References & Citations NASA ADS Google Scholar Semantic Scholar Loading... Data provided by: Bibliographic Tools Bibliographic and Citation Tools Bibliographic Explorer Toggle Bibliographic Explorer (What is the Explorer?) Connected Papers Toggle Connected Papers (What is Connected Papers?) Litmaps Toggle Litmaps (What is Litmaps?) scite.ai Toggle scite Smart Citations (What are Smart Citations?) Code, Data, Media Code, Data and Media Associated with this Article alphaXiv Toggle alphaXiv (What is alphaXiv?) Links to Code Toggle CatalyzeX Code Finder for Papers (What is CatalyzeX?) DagsHub Toggle DagsHub (What is DagsHub?) GotitPub Toggle Gotit.pub (What is GotitPub?) Huggingface Toggle Hugging Face (What is Huggingface?) ScienceCast Toggle ScienceCast (What is ScienceCast?) Demos Demos Replicate Toggle Replicate (What is Replicate?) Spaces Toggle Hugging Face Spaces (What is Spaces?) Spaces Toggle TXYZ.AI (What is TXYZ.AI?) Related Papers Recommenders and Search Tools Link to Influence Flower Influence Flower (What are Influence Flowers?) Core recommender toggle CORE Recommender (What is CORE?) Author Venue Institution Topic About arXivLabs arXivLabs: experimental projects with community collaborators arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs. Which authors of this paper are endorsers? | Disable MathJax (What is MathJax?)