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[Submitted on 10 Sep 2026] Title:Enabling Vision and Cross-Modal Learning for Multimodal Stroke Recurrence Prediction: An Interpretable Two-Step Framework View a PDF of the paper titled Enabling Vision and Cross-Modal Learning for Multimodal Stroke Recurrence Prediction: An Interpretable Two-Step Framework, by Christian Gapp and 10 other authors View PDF HTML (experimental) Abstract:Multimodal stroke recurrence prediction requires effective integration of heterogeneous clinical and imaging data, yet modality imbalance often causes models to over-rely on dominant modalities and underutilize complementary information. While self-supervised pretraining and selective parameter freezing are commonly employed to improve representation learning and fine-tuning stability, their effect on modality contributions and cross-modal behavior in multimodal medical models remains largely unexplored. In this work, we investigate whether image pretraining on 3D CTA scans reduces modality imbalance and improves cross-modal integration for stroke recurrence prediction, a clinically critical task we recently addressed. To this end, two multimodal neural networks are pretrained in a self-supervised manner and subsequently fine-tuned using two distinct freezing strategies. Their performance and modality utilization are compared against both the baseline model from our previous work and models trained entirely from scratch in this study. Our results demonstrate that self-supervised pretraining enables more effective utilization of the multimodal image-tabular dataset, outperforming both the prior baseline and all non-pretrained models. Notably, the best-performing Vision Transformer based neural network successfully overcomes unimodal collapse. Synergy analysis reveals significant interactions between vision and both gender and CHD, suggesting clinically relevant patterns for stroke recurrence. Overall, our findings demonstrate that self-supervised pretraining and strategic fine-tuning support more balanced modality utilization and enable meaningful cross-modal interactions. Code is publicly available at this https URL. Comments: ML-CDS 2026: Multimodal Learning and Fusion Across Scales for Clinical Decision Support, MICCAI 2026, Strasbourg, France Subjects: Computer Vision and Pattern Recognition (cs.CV); Artificial Intelligence (cs.AI) ACM classes: I.2.1 Cite as: arXiv:2609.22271 [cs.CV] (or arXiv:2609.22271v1 [cs.CV] for this version) https://doi.org/10.48550/arXiv.2609.22271 arXiv-issued DOI via DataCite (pending registration) Submission history From: Christian Gapp [view email] [v1] Thu, 10 Sep 2026 13:24:05 UTC (1,799 KB) Full-text links: Access Paper: View a PDF of the paper titled Enabling Vision and Cross-Modal Learning for Multimodal Stroke Recurrence Prediction: An Interpretable Two-Step Framework, by Christian Gapp and 10 other authors View PDF HTML (experimental) TeX Source view license Current browse context: cs.CV new | recent | 2026-09 Change to browse by: cs cs.AI References & Citations NASA ADS Google Scholar Semantic Scholar Loading... Data provided by: Bibliographic Tools Bibliographic and Citation Tools Bibliographic Explorer Toggle Bibliographic Explorer (What is the Explorer?) Connected Papers Toggle Connected Papers (What is Connected Papers?) Litmaps Toggle Litmaps (What is Litmaps?) scite.ai Toggle scite Smart Citations (What are Smart Citations?) Code, Data, Media Code, Data and Media Associated with this Article alphaXiv Toggle alphaXiv (What is alphaXiv?) Links to Code Toggle CatalyzeX Code Finder for Papers (What is CatalyzeX?) DagsHub Toggle DagsHub (What is DagsHub?) GotitPub Toggle Gotit.pub (What is GotitPub?) Huggingface Toggle Hugging Face (What is Huggingface?) ScienceCast Toggle ScienceCast (What is ScienceCast?) Demos Demos Replicate Toggle Replicate (What is Replicate?) Spaces Toggle Hugging Face Spaces (What is Spaces?) Spaces Toggle TXYZ.AI (What is TXYZ.AI?) Related Papers Recommenders and Search Tools Link to Influence Flower Influence Flower (What are Influence Flowers?) Core recommender toggle CORE Recommender (What is CORE?) Author Venue Institution Topic About arXivLabs arXivLabs: experimental projects with community collaborators arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs. Which authors of this paper are endorsers? | Disable MathJax (What is MathJax?)